PULMONARY MECHANICS AND GAS EXCHANGE IN OBESITY Effects of weight reduction and body position
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Prone positioning improves pulmonary function in obese patients during general anesthesia.
We investigated the effects of prone position on functional residual capacity (FRC), the mechanical properties (compliance and resistance) of the total respiratory system, lung and chest wall, and the gas exchange in 10 anesthetized and paralyzed obese (body mass index more than 30 kg/m2) patients, undergoing elective surgery. We used the esophageal balloon technique together with rapid airway ...
متن کاملHIGHLIGHTED TOPIC Pulmonary Physiology and Pathophysiology in Obesity Big breathing: the complex interaction of obesity, hypoventilation, weight loss, and respiratory function
Piper AJ, Grunstein RR. Big breathing: the complex interaction of obesity, hypoventilation, weight loss, and respiratory function. J Appl Physiol 108: 199–205, 2010. First published October 29, 2009; doi:10.1152/japplphysiol.00713.2009.— Obesity places a significant load on the respiratory system, affecting lung volumes, respiratory muscle function, work of breathing, and ventilatory control. D...
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The influence of diaphragmatic position on abnormal gas exchange has been examined to investigate the theory that the impairment in gas exchange in anaesthetized man is caused by disturbance of diaphragmatic mechanics, resulting in abnormalities of dependent lung ventilation. A gas exchange abnormality, probably caused by airway closure in the dependent regions of the lung, was induced in anaes...
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